Product Name :
Emicerfont
Description:
Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.
CAS:
786701-13-1
Molecular Weight:
404.46
Formula:
C22H24N6O2
Chemical Name:
1-1-[1-(4-methoxy-2-methylphenyl)-6-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-ylimidazolidin-2-one
Smiles :
CC1C=C(C2CCN(C=2N=1)C1=CC=C(C=C1C)OC)N1C=CC(=N1)N1CCNC1=O
InChiKey:
JFHJGXQFESYQGY-UHFFFAOYSA-N
InChi :
InChI=1S/C22H24N6O2/c1-14-12-16(30-3)4-5-18(14)26-9-6-17-19(13-15(2)24-21(17)26)28-10-7-20(25-28)27-11-8-23-22(27)29/h4-5,7,10,12-13H,6,8-9,11H2,1-3H3,(H,23,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.|Product information|CAS Number: 786701-13-1|Molecular Weight: 404.46|Formula: C22H24N6O2|Chemical Name: 1-1-[1-(4-methoxy-2-methylphenyl)-6-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-ylimidazolidin-2-one|Smiles: CC1C=C(C2CCN(C=2N=1)C1=CC=C(C=C1C)OC)N1C=CC(=N1)N1CCNC1=O|InChiKey: JFHJGXQFESYQGY-UHFFFAOYSA-N|InChi: InChI=1S/C22H24N6O2/c1-14-12-16(30-3)4-5-18(14)26-9-6-17-19(13-15(2)24-21(17)26)28-10-7-20(25-28)27-11-8-23-22(27)29/h4-5,7,10,12-13H,6,8-9,11H2,1-3H3,(H,23,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Procaine custom synthesis |Shelf Life: ≥12 months if stored properly.Imipramine site |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33210568 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM.|In Vivo:|At concentration of 10 mg/kg, Emicerfont reduces i.c.v. CRF-induced gerbil forepaw treading and marmoset defensive postures. Emicerfont also reduces rat pup ultrasonic vocalization at concentration of 30 mg/kg.|Products are for research use only. Not for human use.|
