Product Name :
CCX354
Description:
CCX354 is an antagonist of CCR1, with anti-inflammatory activity.
CAS:
1010073-75-2
Molecular Weight:
451.91
Formula:
C22H22ClN7O2
Chemical Name:
1-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]ethan-1-one
Smiles :
COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C2NC=CN=2)C2=CC=CN=C12
InChiKey:
ZIMLRKWQDLVPEK-UHFFFAOYSA-N
InChi :
InChI=1S/C22H22ClN7O2/c1-32-18-13-15(4-5-17(18)23)28-9-11-29(12-10-28)19(31)14-30-22-16(3-2-6-26-22)20(27-30)21-24-7-8-25-21/h2-8,13H,9-12,14H2,1H3,(H,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CCX354 is an antagonist of CCR1, with anti-inflammatory activity.|Product information|CAS Number: 1010073-75-2|Molecular Weight: 451.91|Formula: C22H22ClN7O2|Chemical Name: 1-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]ethan-1-one|Smiles: COC1=CC(=CC=C1Cl)N1CCN(CC1)C(=O)CN1N=C(C2NC=CN=2)C2=CC=CN=C12|InChiKey: ZIMLRKWQDLVPEK-UHFFFAOYSA-N|InChi: InChI=1S/C22H22ClN7O2/c1-32-18-13-15(4-5-17(18)23)28-9-11-29(12-10-28)19(31)14-30-22-16(3-2-6-26-22)20(27-30)21-24-7-8-25-21/h2-8,13H,9-12,14H2,1H3,(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Ibalizumab In Vitro |Shelf Life: ≥12 months if stored properly.Bedinvetmab Purity & Documentation |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31905029 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CCX354 shows potent activities in the chemotaxis assay, with IC50 In Vivo:|In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties.|Products are for research use only. Not for human use.|
