Product Name :
Anti-INHBA, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-INHBA, Human antibody is designed for detecting human INHBA specifically. Based on ELISA and/or FCM, Anti-INHBA, Human antibody reacts with human INHBA specifically. | Immunogen: Recombinant human INHBA | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human INHBA | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity.{{30195-30-3} MedChemExpress|{30195-30-3} Protocol|{30195-30-3} Formula|{30195-30-3} custom synthesis} Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.{{1415246-35-3} MedChemExpress|{1415246-35-3} Protocol|{1415246-35-3} Data Sheet|{1415246-35-3} custom synthesis} Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors.PMID:29489192 Activin A mutations are associated with fibrodysplasia ossificans progressive.
Description2 :
Anti-INHBA, Human antibody is designed for detecting human INHBA specifically. Based on ELISA and/or FCM, Anti-INHBA, Human antibody reacts with human INHBA specifically.
Immunogen:
Recombinant human INHBA
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry:1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.