Product Name :
Ibotenic acid
Description:
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
CAS:
2552-55-8
Molecular Weight:
158.11
Formula:
C5H6N2O4
Chemical Name:
(2S)-2-amino-2-(3-oxo-2,3-dihydro-1,2-oxazol-5-yl)acetic acid
Smiles :
N[C@H](C(O)=O)C1=CC(=O)NO1
InChiKey:
IRJCBFDCFXCWGO-BYPYZUCNSA-N
InChi :
InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.|Product information|CAS Number: 2552-55-8|Molecular Weight: 158.11|Formula: C5H6N2O4|Chemical Name: (2S)-2-amino-2-(3-oxo-2,3-dihydro-1,2-oxazol-5-yl)acetic acid|Smiles: N[C@H](C(O)=O)C1=CC(=O)NO1|InChiKey: IRJCBFDCFXCWGO-BYPYZUCNSA-N|InChi: InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5 mg/mL (31.{{Prazosin} web|{Prazosin} Autophagy|{Prazosin} Purity & Documentation|{Prazosin} Data Sheet|{Prazosin} supplier|{Prazosin} Autophagy} 62 mM; Need ultrasonic).{{Afatinib} web|{Afatinib} EGFR|{Afatinib} Biological Activity|{Afatinib} Data Sheet|{Afatinib} manufacturer|{Afatinib} Cancer} H2O : 5 mg/mL (31.PMID:23439434 62 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Ibotenic acid (Ibo) is capable of acting at both NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is involved in Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3±8 μM (n=5) as measured by release of lactate dehydrogenase to the culture media.|Products are for research use only. Not for human use.|
