Product Name :
Gln-AMS TFA
Description:
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM.
CAS:
Molecular Weight:
588.47
Formula:
C17H23F3N8O10S
Chemical Name:
(4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-5-oxopentanamide; trifluoroacetic acid
Smiles :
N[C@@H](CCC(N)=O)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N.OC(=O)C(F)(F)F
InChiKey:
PSKPSIJRHFDWMM-RVUKTNCFSA-N
InChi :
InChI=1S/C15H22N8O8S.C2HF3O2/c16-6(1-2-8(17)24)14(27)22-32(28,29)30-3-7-10(25)11(26)15(31-7)23-5-21-9-12(18)19-4-20-13(9)23;3-2(4,5)1(6)7/h4-7,10-11,15,25-26H,1-3,16H2,(H2,17,24)(H,22,27)(H2,18,19,20);(H,6,7)/t6-,7+,10+,11+,15+;/m0.{{Tegafur-Uracil} MedChemExpress|{Tegafur-Uracil} Purity & Documentation|{Tegafur-Uracil} In Vivo|{Tegafur-Uracil} custom synthesis|{Tegafur-Uracil} Epigenetics} /s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Xanthohumol} web|{Xanthohumol} HSV|{Xanthohumol} Purity & Documentation|{Xanthohumol} In Vivo|{Xanthohumol} manufacturer|{Xanthohumol} Autophagy}
Shelf Life:
≥12 months if stored properly.PMID:35227773
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 µM.|Product information|Molecular Weight: 588.47|Formula: C17H23F3N8O10S|Chemical Name: (4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-5-oxopentanamide; trifluoroacetic acid|Smiles: N[C@@H](CCC(N)=O)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N.OC(=O)C(F)(F)F|InChiKey: PSKPSIJRHFDWMM-RVUKTNCFSA-N|InChi: InChI=1S/C15H22N8O8S.C2HF3O2/c16-6(1-2-8(17)24)14(27)22-32(28,29)30-3-7-10(25)11(26)15(31-7)23-5-21-9-12(18)19-4-20-13(9)23;3-2(4,5)1(6)7/h4-7,10-11,15,25-26H,1-3,16H2,(H2,17,24)(H,22,27)(H2,18,19,20);(H,6,7)/t6-,7+,10+,11+,15+;/m0./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (169.93 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.|Products are for research use only. Not for human use.|
