Product Name :
SORT-PGRN interaction inhibitor 1
Description:
SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM.
CAS:
100957-85-5
Molecular Weight:
258.32
Formula:
C15H18N2O2
Chemical Name:
1-benzyl-3-tert-butyl-1H-pyrazole-5-carboxylic acid
Smiles :
CC(C)(C)C1C=C(C(O)=O)N(CC2C=CC=CC=2)N=1
InChiKey:
IJXYLILRNVOJNF-UHFFFAOYSA-N
InChi :
InChI=1S/C15H18N2O2/c1-15(2,3)13-9-12(14(18)19)17(16-13)10-11-7-5-4-6-8-11/h4-9H,10H2,1-3H3,(H,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM.|Product information|CAS Number: 100957-85-5|Molecular Weight: 258.32|Formula: C15H18N2O2|Chemical Name: 1-benzyl-3-tert-butyl-1H-pyrazole-5-carboxylic acid|Smiles: CC(C)(C)C1C=C(C(O)=O)N(CC2C=CC=CC=2)N=1|InChiKey: IJXYLILRNVOJNF-UHFFFAOYSA-N|InChi: InChI=1S/C15H18N2O2/c1-15(2,3)13-9-12(14(18)19)17(16-13)10-11-7-5-4-6-8-11/h4-9H,10H2,1-3H3,(H,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (387.{{Fomepizole} medchemexpress|{Fomepizole} Metabolic Enzyme/Protease|{Fomepizole} Protocol|{Fomepizole} Data Sheet|{Fomepizole} supplier|{Fomepizole} Autophagy} 12 mM; Need ultrasonic).{{Ezabenlimab} MedChemExpress|{Ezabenlimab} Immunology/Inflammation|{Ezabenlimab} Protocol|{Ezabenlimab} In stock|{Ezabenlimab} custom synthesis|{Ezabenlimab} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23776646 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin.|Products are for research use only. Not for human use.|
