Product Name :
PD-1/PD-L1-IN 5 TFA
Description:
PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.
CAS:
2170209-52-4
Molecular Weight:
532.49
Formula:
C24H19F3N4O5S
Chemical Name:
N-[2-cyano-3-(2, 3-dihydro-1, 4-benzodioxin-6-yl)phenyl]-4H, 5H, 6H, 7H-[1, 3]thiazolo[5, 4-c]pyridine-2-carboxamide; trifluoroacetic acid
Smiles :
N#CC1C(=CC=CC=1C1=CC2OCCOC=2C=C1)NC(=O)C1=NC2CCNCC=2S1.OC(=O)C(F)(F)F
InChiKey:
NXSIYKOVCRSFRA-UHFFFAOYSA-N
InChi :
InChI=1S/C22H18N4O3S.C2HF3O2/c23-11-15-14(13-4-5-18-19(10-13)29-9-8-28-18)2-1-3-16(15)25-21(27)22-26-17-6-7-24-12-20(17)30-22;3-2(4,5)1(6)7/h1-5,10,24H,6-9,12H2,(H,25,27);(H,6,7)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{SiRNA Control} site|{SiRNA Control} Epigenetics|{SiRNA Control} Purity & Documentation|{SiRNA Control} In Vitro|{SiRNA Control} custom synthesis|{SiRNA Control} Cancer}
Additional information:
PD-1/PD-L1-IN 5 TFA is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM.|Product information|CAS Number: 2170209-52-4|Molecular Weight: 532.49|Formula: C24H19F3N4O5S|Chemical Name: N-[2-cyano-3-(2, 3-dihydro-1, 4-benzodioxin-6-yl)phenyl]-4H, 5H, 6H, 7H-[1, 3]thiazolo[5, 4-c]pyridine-2-carboxamide; trifluoroacetic acid|Smiles: N#CC1C(=CC=CC=1C1=CC2OCCOC=2C=C1)NC(=O)C1=NC2CCNCC=2S1.{{Lenacapavir} medchemexpress|{Lenacapavir} HIV|{Lenacapavir} Technical Information|{Lenacapavir} In stock|{Lenacapavir} custom synthesis|{Lenacapavir} Cancer} OC(=O)C(F)(F)F|InChiKey: NXSIYKOVCRSFRA-UHFFFAOYSA-N|InChi: InChI=1S/C22H18N4O3S.PMID:23291014 C2HF3O2/c23-11-15-14(13-4-5-18-19(10-13)29-9-8-28-18)2-1-3-16(15)25-21(27)22-26-17-6-7-24-12-20(17)30-22;3-2(4,5)1(6)7/h1-5,10,24H,6-9,12H2,(H,25,27);(H,6,7)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators.|Products are for research use only. Not for human use.|
