Product Name :
Tr-PEG8-OH
Description:
Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
1144113-16-5
Molecular Weight:
612.75
Formula:
C35H48O9
Chemical Name:
1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol
Smiles :
OCCOCCOCCOCCOCCOCCOCCOCCOC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1
InChiKey:
QMAWPOYSSQJMMG-UHFFFAOYSA-N
InChi :
InChI=1S/C35H48O9/c36-16-17-37-18-19-38-20-21-39-22-23-40-24-25-41-26-27-42-28-29-43-30-31-44-35(32-10-4-1-5-11-32,33-12-6-2-7-13-33)34-14-8-3-9-15-34/h1-15,36H,16-31H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 1144113-16-5|Molecular Weight: 612.75|Formula: C35H48O9|Chemical Name: 1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol|Smiles: OCCOCCOCCOCCOCCOCCOCCOCCOC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1|InChiKey: QMAWPOYSSQJMMG-UHFFFAOYSA-N|InChi: InChI=1S/C35H48O9/c36-16-17-37-18-19-38-20-21-39-22-23-40-24-25-41-26-27-42-28-29-43-30-31-44-35(32-10-4-1-5-11-32,33-12-6-2-7-13-33)34-14-8-3-9-15-34/h1-15,36H,16-31H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Necitumumab} site|{Necitumumab} EGFR|{Necitumumab} Technical Information|{Necitumumab} Description|{Necitumumab} custom synthesis|{Necitumumab} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Parsaclisib} MedChemExpress|{Parsaclisib} PI3K|{Parsaclisib} Purity & Documentation|{Parsaclisib} Formula|{Parsaclisib} manufacturer|{Parsaclisib} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:28440459 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
