igure 4). Most annotated genes in the biological processes category were related towards the inflammatory

igure 4). Most annotated genes in the biological processes category were related towards the inflammatory response and PAK2 manufacturer cellular metabolism. DEGs in comparison group S_Z vs. S_B have been mostly connected with GO terms related to stimulation, biological processes related to lipid synthesis, and metabolism, like the lipid/organic substance catabolic PAK6 site course of action as well as the inflammatory/stimulus response. The majority of DEGs in comparison group K_Z vs. K_B had been linked to stimulationrelated biological processes, G-protein coupled receptor activity, signal transduction-related molecular functions, and cellular elements (cytoskeletal portion, membrane aspect, cytoplasm), such as the acute-phase response, G protein-coupled peptide receptor activity, and transmembrane transporter activity. The majority of DEGs in comparison group H_Z vs. H_B had been assigned with biological processes linked to stimulus, cellular processes, and cellular elements, like cellular response to endogenous stimulus, adverse regulation of biological procedure, regulation of primary metabolic approach, and good regulation of biological approach. The majority of DEGs in comparison group M_Z vs. M_B had been connected with stimulus, immune process, cellular processes, signal transductionrelated molecular functions, and cellular elements, for instance response to abiotic stimulus,Animals 2021, 11,9 ofpositive regulation of neutrophil migration, cellular response to interleukin-1, optimistic regulation of biological course of action, and intracellular signal transduction. The majority of DEGs in comparison group J_Z vs. J_B have been related to stimulus, immune approach, G protein-coupled peptide receptor activity, cellular procedure, and cellular components, such as cellular response to chemical stimulus, G protein-coupled receptor signaling pathway, cellular response to interleukin-1, neutrophil chemotaxis, positive regulation of cellular method, and cell migration. The majority of DEGs in comparison group Z_Z vs. Z_B have been related to cell development, tissue development, cellular approach, and cellular elements, such as striated muscle tissue development, striated muscle cell improvement, muscle structure development, and cell differentiation. Furthermore, the analysis identified 9, 21, 25, 5, 12, and 1 KEGG pathways that have been significantly enriched in DEGs in comparison groups S_Z vs. S_B, K_Z vs. K_B, H_Z vs. H_B, M_Z vs. M_B, J_Z vs. J_B, and Z_Z vs. Z_B, respectively (Figure 5). The drastically enriched pathways in DEGs from comparison group S_Z vs. S_B mainly integrated the complement and coagulation cascades and protein digestion and absorption (Figure six). The pathways drastically enriched in DEGs from comparison group K_Z vs. K_B primarily integrated complement and coagulation cascades, IL-17 signaling pathway, and PI3K-Akt signaling pathway. The substantially enriched pathways in DEGs from comparison group H_Z vs. H_B mostly included the complement and coagulation cascades, protein digestion and absorption, PI3K-Akt signaling pathway, MAPK signaling pathway, and NF-kappa B signaling pathway. The pathways that were drastically enriched within the DEGs from comparison group M_Z vs. M_B mostly integrated protein digestion and absorption, IL17 signaling pathway, TNF signaling pathway, NF-kappa B signaling pathway, NODlike receptor signaling pathway, and HIF-1 signaling pathway. The pathways that were drastically enriched inside the DEGs from comparison group J_Z vs. J_B mainly incorporated