S unclear. Implementation of a prospective surveillance protocol of NIs (KISS) led to a significant

S unclear. Implementation of a prospective surveillance protocol of NIs (KISS) led to a significant reduction in device-days and ventilatory-days, but didn’t lower the absolute variety of NIs. Therefore, device-reduction appeared to become most successful inside the less severely ill individuals only. Reference:1. Bates DW, et al.: Arch Acelarin Intern Med 1999, 159:2553.PNosocomial infection: primary trigger in development of septic complications in the course of postoperative periodE Gyurov, M Milanov, S Milanov, P Neichev Emergency Institute `Pirogov’ ?ICU, 21 Totleben, 1606 Sofia, Bulgaria Objective: To study the frequency of emergence of nosocomial infection in ICU. Style: Retrospective study of information from case records and flow sheets. A single thousand 4 hundred and fifty-one postoperative sufferers admitted to ICU for the duration of 1999?000. Measurements and most important outcomes: Of 1451 individuals in our ICU for the duration of two years, we involve those 613 (42.2 ) who stayed for far more than 72 hours. As outlined by final results from cultures we divided them to 3 groups. Group 1 included 355 (57.9 ) patients without the need of bacterial development. Group two integrated individuals with proved nosocomial infections (NCI). We obtained samples: 898 from urinary catheters (376 optimistic — 41.9 ), 552 from tracheal tube (457 good — 82.8 ), 597 from blood (282 good — 47.two ), 64 intradermal segments from central venous lines (34 good — 53.1 PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20724077 ), and 17 from sputum (15 positive — 88.2 ). Essentially the most widespread location for improvement of NCI in our ICU is respiratory tract. On 5th ICU day the tract became infected in virtually 56 of the sufferers. The key function amongst pathogens played Acinetobacter spp. (27.four ), Citrobacter spp. (20.3 ), P. aeruginosa (12 and Serratia spp. (ten ). The second spot for NCI improvement is reserved for blood-stream infections. Practically the half from the cultures (47.2 ) showed bacterial development. The isolated pathogens were exactly the same: Acinetobacter spp. (19 ), Serratia spp. (16 ), but there was substantial rise in emergence of S. epidermidis in the course of the last year. Its frequency practically equalized that of Acinetobacter spp. The other two primary sources for NCI were urine and CV catheters. They remained on 3rd and 4th areas. Group three integrated individuals with endogenous surgical infections. Within this group we obtained samples from surgical wounds and drainages. In 1999 25.six of cultures showed bacterial growth. In the course of next 2000 this figure rose nearly twice (48.3 ). The leading function played precisely the same Acinetobacter spp., Citrobacter spp., P. aeruginosa, Enterococcus spp. and E. coli. The role of S. epidermidis increased significantly in the course of this period. Conclusions: There was a rise in frequency of nosocomial and secondary endogenous surgical infection in 1999?000. The frequency of Gram-positive pathogens, namely S. epidermidis, almost equalized that of Gram-negative flora as a reason for nosocomial infection. Nosocomial infection remained the main reason for septic complications in postoperative ICU sufferers. Reference:1. E Gyurov, M Milanov, S Milanov: Nosocomial infection: principal trigger in development of septic complications in surgical postoperative individuals. Crit Care 1999, three(suppl 1):P54.PComparative evaluation of sufferers with early-onset versus late-onset nosocomial decrease respiratory tract infections in healthcare ICUS Nseir*, C Di Pomp , P Pronnier*, T Onimus*, S Beague*, F Saulnier*? B Grandbastien, M Erb, D Mathieu*, M Roussel-Delvallez? A Durocher*?*Intensive Care Department, Hygiene Unit, and �Microbiology Laboratory, Calmette Hospita.