G data sets when downloading entire data sets through the 'Download Data' link in the

G data sets when downloading entire data sets through the “Download Data” link in the main menu. Build This indicates the version of the genomic sequence information that was used to assemble the microarray chip in the particular experiment (for example, mm7 or mm8 for the mouse). Builds change slightly as sequence information becomes updated, so the exact base pair position of any given DNA sequence will change as the sequence information becomes annotated. The build information indicated in each data set shows the build used for chromosomal coordinates of probes on the particular array type used. Order ID For Nimblegen data sets only. Cell Line This indicates the name of cell lines employed. At present, D3 [31], TT2 [32] AND 46C [33] are three different established mESCs.Page 8 of(page number not for citation purposes)BMC Bioinformatics 2008, 9:http://www.biomedcentral.com/1471-2105/9/ACBFigure 5 Uploading Your Own Data Set Uploading Your Own Data Set. (A, B) Data file structures. Exemplary tab-delimited text data files for replication timing (A) and transcription (B). (C) A screenshot of the “Data Upload” page.Differentiation State This is the tissue or tissue type represented by the cell line used and grown under the indicated conditions. Currently, there are four such differentiation states:iPS: “Induced Pluripotent Stem Cells” re-programmed from tail-tip fibroblasts derived from a 129xBL-6 hybrid strain of mice to the pluripotent state as described [35].Array Design Name Microarray supplier and catalog number. Data Type Indicates the property being measured in the indicated experiment. At present, replication timing and transcription data are shown. In the future, data for other genomewide properties of chromosomes may be displayed. Contact us to add new types of data such as ChIP-Chip or ChIP-Seq.ESC: Undifferentiated ES cells NPC/EBM9: The 9th day of differentiation following an established neural differentiation protocol that differentiates ESCs via embryoid bodies to Sox1 positive NPCs in conditioned medium [34]. NPC/ASd6: The 6th day of differentiation following an established neural differentiation protocol that differentiates ESCs to Sox1 positive NPCs in monolayer cultures using defined medium [33].Page 9 of(page number not for citation purposes)BMC Bioinformatics 2008, 9:http://www.biomedcentral.com/1471-2105/9/Reference Data sets to be displayed publicly must include a reference. Comments We provide detailed microarray design information here but any Pyrvinium embonate biological activity additional comments can be added. Present or Absent Column For uploading transcription data sets that contain presentabsent calls, specify here. Data Security Level Users can select Public, Private, or er Private. Users can make their published or “in press” data sets publicly available by selecting “Public” and providing a reference under the entry term, Reference. Private data sets are viewable by all registered users with a ReplicationDomain account, while er Private data sets are viewable only by the user who uploaded the data set. Data Starts on Line Usually starts on line 2, with line 1 being the column names.Authors’ contributionsNW and AS are the web site designers, NW designed and programmed interactive web interface and updates/maintains administrative interface, IH generated the data and consulted PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27484364 in all aspects of the design, TR and TY assisted with implementation of the design and communications between biologists and computer scientists, AS designed hardware.