We next employed two different strategies to simultaneously deplete both Pds5 proteins

No 362, No 01/ 012, No 04/014 and The Moulton Charitable Foundation; age 11 years clinical follow-up is funded by the Medical Research Council Grant G0601361. MoBa This work was supported by grants from the Norwegian Research Council, Swedish Medical Society, Jane and Dan Olsson Foundations and Swedish government grants to researchers in the public health service and the European Community’s Seventh Framework Programme, ENGAGE Consortium, grant agreement HEALTH-F42007-201413. The Norwegian Mother and Child Cohort Study was also supported by the Norwegian Ministry of Health and the Ministry of Education and Research, NIH/NIEHS, NIH/NINDS and the Norwegian Research Council/FUGE. We are grateful to all the participating families in Norway who take part in this ongoing cohort study. Researchers interested in using MoBa data must obtain approval from the Scientific Management Committee of MoBa and from the Regional Committee for Medical and Health Research Ethics for access to data and biological material. Researchers are required to follow the terms of an Assistance Agreement containing a number of clauses designed to ensure protection of privacy and compliance with relevant laws. NFBC 1966 and 1986 NFBC1966 and 1986 has received financial support from, e.g. the Academy of GSK126 chemical information Finland, University Hospital Oulu, Biocenter, University of Oulu, PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19821986 Sigrid Juselius Foundation, Finland, the European Commission, European Regional Developmental Fund), NHLBI grant 5R01HL087679-02 through the STAMPEED program, NIH/NIMH, USA, Stanley Foundation, USA, the Medical Research Council, UK and the Welcome Trust, UK. Our most sincere thanks go to all cohort members and their parents. The Section of Investigative Medicine, Imperial College London is funded by grants from the MRC, BBSRC, NIHR, an Integrative Mammalian Biology Capacity Building Award, an FP7-HEALTH- 2009-241592 EuroCHIP grant and is supported by the NIHR Imperial Biomedical Research Centre Funding Scheme. A.I.F.B. is funded by the MRC, EPSRC and Diabetes UK. NTR We thank all participating twin families. N.T.R. is supported by ARRA RC2 2MH08995; the European Research Council; Spinozapremie and Twin-family database for behavior genetics and genomics studies. PANIC We thank the children and their families who participated in The PANIC Study. The study protocol was approved by the Research Ethics Committee of the Hospital District of Northern Savo. All children and their parents gave their informed written consent. The PANIC Study has been financially supported by grants from the Ministry of Social Affairs and Health of Finland, the Ministry of Education and Culture of Finland, the University of Eastern Finland, the Finnish Innovation Fund Sitra, the Social Insurance Institution of Finland, the Finnish Cultural Foundation, the Juho Vainio Foundation, the Foundation for Paediatric Research, the Paulo Foundation, the Paavo Nurmi Foundation, the Diabetes Research Foundation, Kuopio University Hospital and the Research Committee of the Kuopio University Hospital Catchment Area for the State Research Funding. PIAMA The PIAMA birth cohort study is a collaboration of the Institute for Risk Assessment Sciences, University Utrecht, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, Department of Pediatrics, Division of Respiratory Medicine, Erasmus MC -Sophia,