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Ing delivery time windows, and place and relocation expenses, permitting lowing the evaluation of ULS places along with the consequent urban distribution systems conthe evaluation of ULS areas plus the consequent urban distribution systems contemplating sidering optimization criteria in the specific context. Thought of charges are related to the optimization criteria from the distinct context. Considered charges are related to the relocation relocation of facilities, the distance traveled for transportation of goods, as well as the penalizaof facilities, the distance traveled for transportation of goods, as well as the penalization of time tion of time windows violation. problem has problem has not been previously academic windows violation. This place This locationnot been previously studied in the studied in the academic literature, towards the best of our expertise. Additionally, Diloxanide Autophagy implicitly, preferences of literature, for the most effective of our know-how. Furthermore, implicitly, preferences of a functional a functional sort of ULS are viewed as, also as of each and every sort of every single and dimensions form of ULS are thought of, at the same time as stakeholders stakeholders of spacetype of space and dimensions from the infrastructures for the style of logistics networks, as presented within the of the infrastructures for the design and style of logistics networks, as presented inside the taxonomy taxonomy in [25]. This issue is inspired from a reallife predicament located in a mediumin [25]. This problem is inspired from a reallife circumstance located inside a mediumsized city in sized city within the of Pentoxyverine Purity & Documentation Colombia, getting the fourth city fourth city in in country economic the north area north region of Colombia, getting thein the countrythe terms of when it comes to financial importance. Moreover, this delivers an approximation for the real for the of importance. Also, this paper also paper also provides an approximation contextreal context of such issues of urban practice. such issues of urban logistics in logistics in practice. 3. Components and Methods 3. Materials and Strategies The proposed methodology is determined by the interactive, problembased vision with the proposed methodology is according to the interactive, problembased vision of opoperational study [69,70]. Indeed, aimingto deal with a genuine distribution dilemma, the erational study [69,70]. Indeed, aiming to take care of distribution trouble, the problemsolving process needs to represent suitably the reality we take care of, and to perform problemsolving method wants to represent suitably the reality we take care of, and to perform that it is important to create a framework that is connected and in comparison to the reality it framework that may be associated and in comparison to the reality that it is important it aims torepresent. This results in the application from the Ackoff’s problem solving cycle, represent. This results in the application aims to Ackoff’s issue solving cycle, which could be defined as follows from Ackoff’s [69] considerations (see Figure 1). which can be defined as follows from Ackoff’s [69] considerations (see Figure 1).Figure 1. The problem solving cycle of Ackoff extended and adapted (authors’elaboration from Figure 1. The issue solving cycle of Ackoff extended and adapted (authors’elaboration from GonzalezFeliu’s [70], considerations). GonzalezFeliu’s [70], considerations).Additional precisely, this function aims to model a reality, so for this objective, it is very important begin from a field representing this reality, observe it, after which conceive initial the representation with the decisio.

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Author: M2 ion channel