Product Name :
Argifin
Description:
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively.
CAS:
243975-37-3
Molecular Weight:
675.69
Formula:
C29H41N9O10
Chemical Name:
(2R,5S,8S,11S,15S)-5-[3-({amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid
Smiles :
C[C@H]1NC(=O)C[C@H](NC(=O)C[C@H](NC(=O)[C@H](CC2C=CC=CC=2)N(C)C(=O)[C@H](CCCN=C(N)NC(=O)NC)NC1=O)C(O)=O)C(O)=O
InChiKey:
UHBHXSDKGLPPGO-HTDHLNIYSA-N
InChi :
InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18+,19+,20+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tisotumab} medchemexpress|{Tisotumab} Antibody-drug Conjugate/ADC Related|{Tisotumab} Purity & Documentation|{Tisotumab} In Vitro|{Tisotumab} manufacturer|{Tisotumab} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively.|Product information|CAS Number: 243975-37-3|Molecular Weight: 675.69|Formula: C29H41N9O10|Chemical Name: (2R,5S,8S,11S,15S)-5-[3-({amino[(methylcarbamoyl)amino]methylidene}amino)propyl]-8-benzyl-2,7-dimethyl-3,6,9,13,17-pentaoxo-1,4,7,10,14-pentaazacycloheptadecane-11,15-dicarboxylic acid|Smiles: C[C@H]1NC(=O)C[C@H](NC(=O)C[C@H](NC(=O)[C@H](CC2C=CC=CC=2)N(C)C(=O)[C@H](CCCN=C(N)NC(=O)NC)NC1=O)C(O)=O)C(O)=O|InChiKey: UHBHXSDKGLPPGO-HTDHLNIYSA-N|InChi: InChI=1S/C29H41N9O10/c1-15-23(41)35-17(10-7-11-32-28(30)37-29(48)31-2)25(43)38(3)20(12-16-8-5-4-6-9-16)24(42)36-19(27(46)47)14-22(40)34-18(26(44)45)13-21(39)33-15/h4-6,8-9,15,17-20H,7,10-14H2,1-3H3,(H,33,39)(H,34,40)(H,35,41)(H,36,42)(H,44,45)(H,46,47)(H4,30,31,32,37,48)/t15-,17+,18+,19+,20+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ensitrelvir} medchemexpress|{Ensitrelvir} SARS-CoV|{Ensitrelvir} Protocol|{Ensitrelvir} References|{Ensitrelvir} custom synthesis|{Ensitrelvir} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:24576999 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Argifin inhibits L. cuprina chitinase with IC50 values of 3.7 μM at 37 ºC and 0.10 μM at 20 ºC.|In Vivo:|Argifin has the ability to inhibit L. cuprina molting.|Products are for research use only. Not for human use.|
