Ependent variable; model (n = 2118), sum R = 0.350, sum R2 = 0.123; two Biomarkers adjusted for

Ependent variable; model (n = 2118), sum R = 0.350, sum R2 = 0.123; 2 Biomarkers adjusted for cholesterol (mol/mmol) all measured biomarkers such as cholesterol have been assessed as covariates inside the initial model (n = 2118), have been assessed in the initial model (n = 1993); sum R = 0.348, sum R2 = 0.121. Regression coefficient B sum R = 0.350, sum R2 = 0.123; 2 represents greater (+)/lower (-) Biomarkers adjusted for cholesterol ( ol/mmol) were assessed inside the initial age (years) with every single unit (mol/L or mol/mmol) improve in model (n = 1993); sum R = 0.348, sum R2 = 0.121. Regression coefficient B represents greater (+)/lower (-) age respective compounds, e.g., per 1 mol/L enhance in lycopene, mean age was six.six years decrease (-6.638 (years) with every unit ( ol/L or ol/mmol) improve in respective compounds, e.Osteopontin/OPN Protein Source g., per 1 ol/L raise in lycopene, mean age was 6.6 years decrease (-6.638 years). years).(mol/L) 1 51.35 49.36, 53.34 Table 4. Association of carotenoids and -tocopherol with age. Lycopene -6.638 -7.778, -5.499 -0.248 0.059 Tocopherol 0.229, 0.348 Partial R 0.208 0.042 (B) 0.289 95 CI (R2 ) Carotene -5.761 -8.012, -3.524 -0.112 0.011 51.35 49.36, 53.34 ( ol/L) 1 Cryptoxanthin 5.062 -7.778, -5.499 3.302, six.823 -0.248 0.125 0.011 Lycopene -6.638 0.059 two (mol/mmol) 50.64, 55.41 -Tocopherol 0.28953.03 0.229, 0.348 0.208 0.042 -Carotene -5.761 0.112 0.011 Lycopene/Cholesterol -39.15 -8.012, -3.524 -45.64, -32.65 –0.256 0.076 -Cryptoxanthin 0.125 0.011 Tocopherol/Cholesterol five.0621.394 three.302, six.823 1.009, 1.780 0.157 0.022 2 53.03 ( ol/mmol) Carotene/Cholesterol -36.32 50.64, 55.41 -48.68, -23.96 -0.128 0.011 Lycopene/Cholesterol -39.15 0.076 Cryptoxanthin/Cholesterol 25.85 -45.64, -32.65 16.21, 35.49 -0.256 0.117 0.0.001 0.001 0.001 p 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.Figure 1. Imply lycopene across age groups. The black line indicates the mean plasma concentration of Figure 1. Mean lycopene across age groups. The black line indicates the mean plasma concentration of lycopene in the different age groups (n = 2118). lycopene in the distinctive age groups (n = 2118).Nutrients 2016, 8, 614 Nutrients 2016, 8,9 of9 of(a)three.Age(b) Season(c) Country2.Lycopene [ ol/L] Tocopherol [ ol/L] Carotene [ ol/L] Cryptoxanthin [ ol/L]2.FGF-9 Protein site 1.PMID:24202965 1.0.0.010 1.0.0.0.0.0 1.1.0.0.Figure 2. Micronutrient concentrations by age, season, and nation. Box-plots of plasma lycopene, Figure 2. Micronutrient concentrations by age, season, and country. Boxplots of plasma lycopene, tocopherol, carotene, and cryptoxanthin by (a) age in fiveyear age groups; (b) season; and (c) (c) -tocopherol, -carotene, and -cryptoxanthin by (a) age in five-year age groups; (b) season; and nation (AUT, Austria; BEL, Belgium; GER, Germany; GRE, Greece; ITA, Italy; POL, Poland). Intense country (AUT, Austria; BEL, Belgium; GER, Germany; GRE, Greece; ITA, Italy; POL, Poland). Extreme values are integrated in analyses but not shown in the figure. values are incorporated in analyses but not shown in the figure.Nutrients 2016, 8,10 ofCholesterol was hugely and positively associated with -tocopherol ( p two = 0.266; Table A1). Lower plasma lycopene was connected with overweight and/or obesity, use of vitamin supplements, everyday fruit and higher frequency in juice consumption, under no circumstances consuming French fries and seldom but in addition everyday meat servings. The frequent consumption of fruit or vegetables.